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Publisher ‏ : ‎ Springer; 2007th edition (October 12, 2006)
Language ‏ : ‎ English
Hardcover ‏ : ‎ 312 pages
ISBN-10 ‏ : ‎ 038732464X
ISBN-13 ‏ : ‎ 978-0387324647
Item Weight ‏ : ‎ 1.24 pounds
Dimensions ‏ : ‎ 6.14 x 0.75 x 9.21 inches

Herpesviruses are a common family of viruses that can cause a variety of diseases, ranging from cold sores to chickenpox to more serious conditions like shingles and genital herpes. One of the key characteristics of herpesviruses is their ability to establish latency, meaning they can remain dormant in the body for extended periods of time before reactivating and causing symptoms.

There are several strategies that herpesviruses use to maintain latency in the host. One of the most common mechanisms is the establishment of latent infection in sensory neurons. After the initial infection, the virus travels along nerve fibers to the cell bodies of sensory neurons, where it can remain dormant for long periods of time. This allows the virus to evade detection by the immune system and avoid being cleared from the body.

Another strategy employed by herpesviruses is the ability to periodically reactivate and replicate in the host. When conditions are right, such as during times of stress or immunosuppression, the virus can be triggered to reactivate and start producing new viral particles. This can lead to the recurrence of symptoms and the spread of the virus to new hosts.

Overall, the latency strategies of herpesviruses are complex and multifaceted, allowing them to persist in the host for extended periods of time and cause recurrent infections. Understanding these strategies is crucial for developing effective treatments and vaccines to combat these persistent viruses.
#Latency #Strategies #Herpesviruses