Former Biggest Loser trainer Jillian Michaels has sounded the alarm on GLP-1 drugs like Ozempic, urges people to ‘try anything else’ to lose weight.
Michaels, 50, shared her thoughts on the popular drugs taking Hollywood by storm during an exclusive interview with DailyMail.com in New York City this month.
Over the past few years, GLP-1 medications, which have historically been used to treat type 2 diabetes, have become extremely popularized as a weight-loss aid after they were approved by the FDA.
Ozempic contains a compound called semaglutide, which ‘mimics the GLP-1’ hormone, according to UCLA Health – a hormone that can work with your brain to suppress your appetite and make you feel fuller more quickly.
When it’s taken in a high dose, combined with diet and exercise, it can help people lose weight.
It’s particularly taken off in Hollywood, with celebrities like Oprah Winfrey, Sharon Osbourne, and Rebel Wilson all having admitted to taking a weight-loss drug.
But Michaels, who helped people lose hundreds of pounds without weight loss medication or surgery on The Biggest Loser, is not exactly a fan.
‘Everything with medication, for me personally, is a cost-benefit analysis,’ Michaels told DailyMail.com exclusively.

Former Biggest Loser trainer Jillian Michaels has sounded the alarm on GLP-1 drugs like Ozempic, urges people to ‘try anything else’ to lose weight

Over the past few years, GLP-1 medications, which have historically been used to treat type 2 diabetes, have become extremely popularized as a weight-loss aid
She made the analogy to that of antibiotics, explaining that she ‘doesn’t want to live in a world’ without them, but doesn’t like to take them unless it’s ‘life or death,’ citing side effects.
Michaels said that she looks at GLP-1 medications in a ‘similar fashion.’
‘In other words, if you’re morbidly obese, if you’ve tried everything, generally, there will also be a deep psychological component, a physiological addiction, if you have other elements of your health that have failed you, in this cost-benefit analysis, you will absolutely twist my arm,’ she admitted.
However, she still does not encourage people to take them due to some recent studies, like one done by Prime Therapeutics which showed that a high percentage of users no longer took the drug after one year.
Michaels claimed that the drugs are ‘not sustainable’ and have side effects that you ‘won’t out-run over time.’
While the medications are FDA-approved for treating Type 2 diabetes, Wegovy and Zepbound are the only two approved by the FDA for weight loss alone.
Doctors, patients, and studies have reported various side effects of the drugs.
The weight loss drug makers face as many as 10,000 lawsuits due to severe side effects like stomach paralysis, tears in patients’ food pipes, blindness, and suicidal thoughts.

But Michaels, who helped people lose hundreds of pounds without medical intervention on The Biggest Loser, is not exactly a fan

Michaels claimed that the drugs are ‘not sustainable’ and have side effects that you ‘won’t out-run over time

In a February 2023 interview with People, the mom-of-two claimed that she had convinced multiple friends to get off the drug
‘If you’re taking this to lose 20 pounds, 30 pounds, 45, 50 pounds, I would strongly suggest trying anything else,’ Michaels told DailyMail.com.

The weight loss drug makers face as many as 10,000 lawsuits due to severe side effects like stomach paralysis, tears in patients’ food pipes, blindness, and suicidal thoughts
This isn’t the first time that the trainer has slammed the medications.
In a February 2023 interview with People, the mom-of-two claimed that she had convinced multiple friends to get off the drug.
She alleged you can have a ‘rebound’ weight gain after stopping the medicine.
‘Once they get off of the drug, it does the rebound effect,’ she told the outlet at the time.
‘So you’re not gaining anything. You get off the drug in a year and go all the way back. You’ve not learned anything. You’ve not built any physical strength or endurance. You haven’t learned how to eat healthy.’
Former Biggest Loser trainer Jillian Michaels recently took to social media to slam the weight loss medication Ozempic, advising her followers to “try anything else” instead.
In a post on Instagram, Michaels expressed her concerns about the potential side effects of Ozempic, which is a prescription medication used to treat obesity. She cited research showing a link between the drug and an increased risk of pancreatitis and thyroid tumors.
“Please, try anything else before you resort to this potentially dangerous medication,” Michaels wrote. She went on to recommend alternative methods for weight loss, such as diet and exercise, as safer and more sustainable options.
Michaels’ strong stance against Ozempic has sparked debate among her followers, with some praising her for speaking out against potentially harmful medications, while others defend the drug’s effectiveness in helping with weight loss.
Regardless of where you stand on the issue, it’s clear that Michaels’ message has struck a chord with many people who are struggling with their weight. As always, it’s important to consult with a healthcare professional before starting any new weight loss regimen, especially when considering prescription medications like Ozempic.
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