Tag: ONSET

  • Researchers identify 36 genes related to the onset and development of bipolar disorder


    The study was led by the Bipolar Disorder Working Group at the Psychiatric Genomics Consortium, an international group made up of more than 800 researchers from 40 countries in which professionals from IDIBAPS-Hospital Clínic and Hospital Vall d’Hebron participate, all of them researchers from CIBER de Salud Mental (CIBERSAM).

    A disorder with a high genetic component

    Bipolar disorder is a chronic mental disorder that affects between 40 and 50 million people worldwide and is characterised by the alternation of depressive episodes and episodes of mania or hypomania (euphoric or irritable moods). It can have a profound impact on daily life if not treated properly and poses a significant public health problem.

    It has a substantial genetic basis, with an estimated heritability of between 60% and 80%. However, identifying the specific genes involved in this disorder has been a great challenge due to its complexity, as it combines genetic and environmental factors.

    Genetic characterisation of bipolar disorder

    The international group conducted a meta-analysis of several genome-wide association studies, combining their results to more accurately identify the genetic variants associated with a disease or a trait. In total, more than 158,000 patients with bipolar disorder and 2.8 million people without the disorder were included and the genes of the two groups were compared to decipher the existing differences. The most important feature is that people from all six inhabitable continents were included for the first time.

    The study identified 337 variants of genome-wide significance (GWS) that are mutually independent and grouped into 298 specific regions of the genome (loci). This identification is four times larger than that of any previous study. These genetic variants are related to the causes of the disorder, as well as to brain plasticity and signal transmission.

    By combining the results of advanced genetic mapping techniques, like fine-mapping and other strategies to link genetic variants with specific genes, the researchers identified 36 reliable genes related to the causes or development of bipolar disorder.

    The researchers also found genetic differences, depending on the patients’ subtype of bipolar disorder. For instance, they found a greater genetic relationship with schizophrenia in the cohorts with a large proportion of patients with type 1 bipolar disorder. In the cohort with more cases of patients with type 2 bipolar disorder, they detected a greater genetic correlation with major depressive disorder and attention deficit hyperactivity disorder (ADHD).

    ‘With this study, we have taken a big step forward to better understand how this disorder functions and what causes it. Given a little more time, we also hope to develop new and better treatments for it’, says Dr Eduard Vieta, the head of Hospital Clínic’s Psychiatry Service and of the IDIBAPS research group Bipolar and depressive disorders.

    Study reference:

    Characterising the genetic landscape of bipolar disorder yields novel biological insights. Nature. DOI: https://www.nature.com/articles/s41586-024-08468-9



    Researchers have recently made a breakthrough in understanding bipolar disorder by identifying 36 genes that are related to the onset and development of the disorder. This discovery sheds light on the complex genetic factors that contribute to bipolar disorder and may lead to new avenues for treatment and management.

    Bipolar disorder is a mental health condition characterized by extreme mood swings, ranging from manic episodes of high energy and euphoria to depressive episodes of sadness and hopelessness. It affects millions of people worldwide and can have a significant impact on daily functioning and quality of life.

    By pinpointing these 36 genes, researchers have taken a crucial step towards unraveling the genetic basis of bipolar disorder. Understanding the role of these genes in the development of the disorder could help identify individuals at risk, improve early detection, and ultimately lead to more targeted and effective treatments.

    This groundbreaking research opens up new possibilities for personalized medicine and precision psychiatry in the treatment of bipolar disorder. As scientists continue to delve deeper into the genetic underpinnings of mental health conditions, we are one step closer to developing more tailored and effective interventions for those living with bipolar disorder.

    Tags:

    1. Bipolar disorder genes
    2. Genetic factors in bipolar disorder
    3. Bipolar disorder research
    4. Bipolar disorder genetics study
    5. Genetic markers for bipolar disorder
    6. Bipolar disorder gene identification
    7. Genes linked to bipolar disorder
    8. Bipolar disorder genetic research
    9. Bipolar disorder gene discovery
    10. Genetic variations in bipolar disorder

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  • ONSET MXGTW1 HOBO GATEWAY COMMUNICATIONS HUB 900-00070 REMOTE MONITORING SENSOR

    ONSET MXGTW1 HOBO GATEWAY COMMUNICATIONS HUB 900-00070 REMOTE MONITORING SENSOR



    ONSET MXGTW1 HOBO GATEWAY COMMUNICATIONS HUB 900-00070 REMOTE MONITORING SENSOR

    Price : 349.99

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    Introducing the ONSET MXGTW1 Hobo Gateway Communications Hub 900-00070 for Remote Monitoring Sensor Systems

    Are you looking for a reliable and efficient solution for remote monitoring of sensor data? Look no further than the ONSET MXGTW1 Hobo Gateway Communications Hub 900-00070. This cutting-edge device is designed to provide seamless communication between your sensors and the cloud, allowing you to monitor and analyze data from anywhere in the world.

    The MXGTW1 Hobo Gateway is easy to set up and use, making it the perfect choice for both beginners and experienced users. With its robust construction and advanced features, this gateway is built to withstand even the harshest conditions, ensuring that your data is always secure and accessible.

    Whether you need to monitor temperature, humidity, light levels, or any other environmental data, the ONSET MXGTW1 Hobo Gateway Communications Hub 900-00070 has you covered. Don’t wait any longer to take your remote monitoring to the next level – invest in the MXGTW1 today and experience the difference for yourself.
    #ONSET #MXGTW1 #HOBO #GATEWAY #COMMUNICATIONS #HUB #REMOTE #MONITORING #SENSOR, Remote Monitoring

  • Onset HOBO U30 Remote Monitoring, Data Logger, Weather Station U30-GSM

    Onset HOBO U30 Remote Monitoring, Data Logger, Weather Station U30-GSM



    Onset HOBO U30 Remote Monitoring, Data Logger, Weather Station U30-GSM

    Price : 69.99

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    The Onset HOBO U30 Remote Monitoring, Data Logger, Weather Station U30-GSM is a powerful and versatile tool for monitoring environmental conditions in remote locations. With its integrated GSM cellular modem, the U30-GSM can transmit data wirelessly to a secure cloud-based server, allowing users to access real-time data from anywhere in the world.

    The U30-GSM is equipped with a wide range of sensors, including temperature, humidity, barometric pressure, wind speed, and rainfall, making it ideal for a variety of environmental monitoring applications. Its rugged design and long battery life make it suitable for use in harsh outdoor environments, while its user-friendly software interface allows for easy configuration and data analysis.

    Whether you need to monitor weather conditions at a remote research site, track environmental conditions in a remote industrial facility, or ensure regulatory compliance at a remote monitoring station, the Onset HOBO U30-GSM Remote Monitoring, Data Logger, Weather Station is the perfect solution. With its reliable performance, advanced features, and easy-to-use interface, the U30-GSM is the ultimate tool for remote environmental monitoring.
    #Onset #HOBO #U30 #Remote #Monitoring #Data #Logger #Weather #Station #U30GSM, Remote Monitoring

  • Onset HOBO U30 Remote Monitoring, Data Logger, Weather Station U30-GSM-000 …

    Onset HOBO U30 Remote Monitoring, Data Logger, Weather Station U30-GSM-000 …



    Onset HOBO U30 Remote Monitoring, Data Logger, Weather Station U30-GSM-000 …

    Price : 199.00

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    Are you looking for a reliable and easy-to-use remote monitoring solution for your environmental data? Look no further than the Onset HOBO U30 Weather Station U30-GSM-000! This all-in-one data logger and weather station is the perfect tool for monitoring a wide range of environmental parameters, including temperature, humidity, rainfall, wind speed, and more.

    With its built-in GSM modem, the U30 Weather Station allows you to access your data remotely, making it ideal for monitoring remote or hard-to-reach locations. The included HOBOlink software makes it easy to set up and manage your monitoring system, giving you real-time access to your data from anywhere in the world.

    Whether you’re a researcher, environmental consultant, or just someone who wants to keep an eye on the weather, the Onset HOBO U30 Weather Station U30-GSM-000 is the perfect solution for all your remote monitoring needs. Don’t wait, get yours today and start monitoring with confidence!
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  • HOBO Remote Monitoring System Onset U30 – weather data logger

    HOBO Remote Monitoring System Onset U30 – weather data logger



    HOBO Remote Monitoring System Onset U30 – weather data logger

    Price : 35.87

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    Introducing the HOBO Remote Monitoring System Onset U30 – your all-in-one solution for tracking and analyzing weather data!

    With the Onset U30, you can remotely monitor and record temperature, humidity, wind speed, and more with ease. This weather data logger is perfect for a wide range of applications, from agriculture and environmental research to HVAC system monitoring and building management.

    Stay informed and make informed decisions with the reliable and accurate data provided by the Onset U30. Say goodbye to manual data collection and hello to real-time monitoring from anywhere, at any time.

    Upgrade your weather monitoring capabilities with the HOBO Remote Monitoring System Onset U30 – the ultimate tool for tracking and analyzing weather data. #HOBO #weatherdatalogger #remotemonitoring #OnsetU30
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  • ONSET HOBO U30 Remote Monitoring System Station Box and Board ONLY

    ONSET HOBO U30 Remote Monitoring System Station Box and Board ONLY



    ONSET HOBO U30 Remote Monitoring System Station Box and Board ONLY

    Price : 144.95

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    Are you looking for a reliable and efficient remote monitoring system for your industrial applications? Look no further than the ONSET HOBO U30 Remote Monitoring System Station Box and Board ONLY.

    This system is designed to provide accurate and real-time data monitoring for a wide range of environmental conditions. The station box and board are built to withstand harsh environments and ensure reliable performance.

    With the ONSET HOBO U30 Remote Monitoring System, you can easily monitor temperature, humidity, voltage, and more from anywhere in the world. The easy-to-use interface allows for seamless data logging and analysis, making it the perfect solution for remote monitoring needs.

    Don’t settle for subpar monitoring systems, invest in the ONSET HOBO U30 Remote Monitoring System Station Box and Board ONLY for unparalleled data accuracy and reliability.
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  • NEW! ONSET MXGTW1 HOBO GATEWAY COMMUNICATIONS HUB 900-00070 REMOTE MONITORING

    NEW! ONSET MXGTW1 HOBO GATEWAY COMMUNICATIONS HUB 900-00070 REMOTE MONITORING



    NEW! ONSET MXGTW1 HOBO GATEWAY COMMUNICATIONS HUB 900-00070 REMOTE MONITORING

    Price : 350.00

    Ends on : N/A

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    Introducing the new Onset MXGTW1 Hobo Gateway Communications Hub 900-00070!

    Stay connected and monitor your data remotely with this state-of-the-art communications hub. The Onset MXGTW1 Hobo Gateway allows you to access and view your data from anywhere, anytime, making it easier than ever to stay on top of your monitoring needs.

    With its user-friendly interface and reliable performance, this gateway is the perfect solution for remote monitoring applications. Keep track of your data with ease and peace of mind, knowing that you can access it whenever you need to.

    Don’t miss out on the opportunity to streamline your monitoring process with the Onset MXGTW1 Hobo Gateway Communications Hub 900-00070. Order yours today and experience the convenience of remote monitoring like never before! #OnsetMXGTW1 #HoboGateway #RemoteMonitoring.
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